Patents

An in-vivo, intraoperative probe for brain tumour margin delineation and methods thereof

Inventors:

Hardik J Pandya, Arjun B S, Anil Vishnu G. K., Gokul A M, Arun Baby, Shilpa Rao, Vikas V, Manish Beniwal and Anita Mahadevan.

Abstract:

The invention involves an intra-operative, in-vivo probe that can delineate tumour margin during brain tumour resection. The probe can increase the extent of resection and the probability of attaining gross tumour resection, thus leading to improved survival rates, as well as quality of life among the patients after surgical intervention. It also can address issues such as brain plasticity thereby enhancing the accuracy of brain tumour resection. With real-time results, the probe can aid in intra-operative decision making. The probe, associated electronics and interface units are unique by means of the sensing modality they use. The probe is integrated with biochips or sensors or microarrays that are fabricated using technologies like MEMS or nanoimprint or screen printing or any of the other lithography-based processes or technology. These sensors can be multifunctional and thereby measure multiple parameters based on different principles for attaining the best accurate results. The probe design is such that it can reach out to complex surfaces and can be operated manually by hand as well as robotically. A virtual representation of tumour margin can be obtained using the data obtained from the probe and will be displayed on the interface unit for assisting the surgeon in resection.

Status:

Filed

Patent Application number:

TEMP/E1/24832/2020- CHE

Date of Filing:

30th May 2020

A handheld diagnostic tool for grading stenosis in pediatric upper airway and methods for characterizing the same.

Inventors:

Hardik J Pandya, Alekya B, Bhushan V, V S N Sitaram Gupta V, Arjun B S, Kevin Abhishek, S Siddesh Shenoy, Sanjay Rao and Mayur Bhuva.

Abstract:

The invention pertains to a sensor integrated diagnostic tool for management of pathological airway in pediatric population. The tool can be used for characterizing the tracheal obstruction, such as stenosis, of varying grades and anomaly types. The tool is a combination of an array of flow sensors and an unfurling actuator with radial arms that houses tactile sensors at the tip of the arm. The flow sensor array yields airflow patterns across various segments of the tracheobronchial tree and the unfurling actuator measures patency with tactile sensors capable of distinguishing between malacic and healthy tissue. The unfurler has radial arms that remain coiled inside the cylindrical casing at the distal tip. Upon actuation, the arms uncoil radially outward. The movement of the radial arms causes the tactile sensors to contact the tracheal walls and gives a measure of the tracheal diameter.

Status:

Filed

Indian Provisional Patent Application number:

TEMP/E-1/30202/2020-CHE

Date of Filing:

26th June 2020

International application number: 

PCT/IB2021/054690

Date of Filing:

28th May 2021

Apparatus for High-Throughput Rapid Antibiotic Susceptibility Testing and Methods Thereof.

Inventors:

Hardik J Pandya, Anil Vishnu G K, Bhagaban Behera, Alekya B, Arun Baby, Saeed Rila B C, Arjun B S, Midhun C Kachappilly, Prathik BH, Dipshikha Chakravortty and Nagasuma Chandra.

Abstract:

The present disclosure provides a system for rapid antibiotic susceptibility testing. The system comprises portable electronic platform integrated with a cartridge containing a microfluidic chip, interdigitated electrodes, and microheaters for rapid, real-time, and label-free antibiotic susceptibility testing based on electrical sensing modality. A portable impedance analyser with a port is configured for holding the cartridge containing the microfluidic chip for AST testing.

Status:

Filed

Patent Application number:

TEMP/E-1/26941/2020-CHE

Date of Filing:

10th June 2020

Smart Wearable Device for Continuous Monitoring of Body Temperature and Blood Oxygen Saturation.

Inventors:

Hardik J Pandya, Jagannathan Gopalakrishnan, Sonal Asthana, Vishnu Kurpad, Anil Vishnu G K, Midhun C. Kachappilly and Arjun B S.

Abstract:

A smart wearable device for monitoring health status is disclosed, comprising a temperature sensor and a blood oxygen saturation (SpO2) sensor. The temperature sensor senses temperature of the user whereas the SpO2 sensor senses blood oxygen saturation and heart rate of the user. The device includes a control unit that receives at least one of temperature, heart rate, and SpO2 of the user from the temperature sensor and SpO2 sensor. The control unit also determines whether at least one of temperature, heart rate, and SpO2 falls below respective threshold. When the at least one of temperature, heart rate, and SpO2 falls below the threshold, the control unit generates an alert signal to alert the nearest health services about the health status of the user.

Patent Application number:

TEMP/E-1/29841/2020-CHE

Date of Filing:

25th June 2020

Apparatus and System for Rapid Diagnosis of Malignant Lesions from Biopsy Tissues for Use Inside the Operation Room.

Inventors:

Hardik J Pandya, Anil Vishnu G K, Bhagaban Behera, Saeed Rila, Midhun C Kachappilly, Arun Baby and Annapoorni Rangarajan.

Abstract:

The present disclosure provides a system for rapid diagnosis of malignant lesions from biopsy tissue. The system comprises table-top platform integrated with microsensors and electronic modules for label-free and rapid phenotyping of extracted biopsy tissues using multiple modalities for a quick diagnosis, and to identify the margin for use inside the operation room. A multiple logistic regression model takes all the physical parameters measured as input variables to accurately predict the diagnosis. The electrical resistivity, thermal conductivity and mechanical stiffness of the extracted biopsy tissues are measured and used for performing the diagnostic delineation. The computations are performed on-board and the entire system can be controlled and actuated using a smart phone

Patent Application number:

TEMP/E1/33093/2020-CHE

Date of Filing:

30th May 2020

Point of Care Diagnostic Systems 

Inventors:

Abhay Chopada, Hardik J Pandya, Nilesh Jain, et al.

Indian patent application filing no.:

202021020250

Date of Filing:

May 14, 2020

Personal Auscultation Device for Medical Analysis (PADMA)

Inventors:

Abhay Chopada, Hardik J Pandya, Nilesh Jain, et al.

Indian patent application filing no.:

202021016743

Date of Filing:

April 17, 2020

Non-invasive test kit for rapid detection and screening infectious disease in individuals

Inventors:

Hardik J Pandya, Jagannathan Gopalkrishnan, Anil Vishnu G K, Midhun C. Kachappilly, Sudarshan Jagannathan, Akhil Mohan and Uttam M. Pal.

Indian patent application filing no.:

202041022006

Date of Filing:

May 26, 2020

Portable Multi-Parameter Cancer Diagnostic Device

Inventors:

Jaydev P. Desai, Hardik J Pandya and Kihan Park.

Provisional US Patent Application No.:

62/112867

Date of Filing:

6th February 2015.

An Improved Micro-heater in Silicon Substrate using Trench Formation, Backfill and CMP

Inventors:

Sudhir Chandra and Hardik J Pandya.

Indian patent application filing no.:

1619/DEL/2012

Date of Filing:

29th May 2012

MEMS Based Energy Efficient Sensors on Oxide Platform in Silicon Substrate for Detection of Volatile Organic Compounds and Gases

Inventors:

Sudhir Chandra and Hardik J Pandya.

Indian patent application filing no.:

1802/DEL/2012

Date of Filing:

12th June 2012