Congratulations Suman on successfully defending your Ph.D. Thesis!

• Post by: beeslab
• January 11, 2023
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Suman worked on the Design and Development of Implantable Electrode Arrays for Recording Signals from Rat’s Brains.

These implantable microelectrode arrays were fabricated to record ECoG and sEEG signals from the somatosensory cortex of rats’ brains. The brain activities at normal, induced epileptic (by convulsant or electrical stimulation), and recovered (after antiepileptic drug (AED) administration) conditions were acquired. The work combines microfabrication, signal processing, and understanding neuroscience using the fabricated array from the rat epilepsy model. The reported high-density 32-channel microelectrode arrays developed by Suman exhibited ECoG acquisition with higher spatial resolution under different neurophysiological conditions. Understanding the effect of antiepileptic drugs during seizures in rat models from the acquired brain activities was demonstrated in rat models, which may be used to understand the efficacy of AEDs.

He also demonstrated a 10-channel biodegradable microelectrode array recording of baselines, epileptic activities, and somatosensory evoked potentials using chronic studies. This custom-design microelectrode array can be a potential solution to avoid retrieval surgeries associated with implantable devices in the future. Additionally, a silicon-based 13-channel microneedle electrode array was designed and fabricated to study the variation of the local field potentials from the somatosensory cortical columns under epileptic and normal conditions in acute studies.

These works also demonstrate OpenBCI Cyton Daisy Biosensing Board as an affordable and efficient alternative acquisition system that was not reported for in vivo recording in animal experiments.

All from BEES Lab wish Suman great success in his future endeavors!